Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 12/20 | 1.00 |
| ▸ | HTT | P42858 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | LMNA | P02545 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.85 |
| ▸ | RAB9A | P51151 | 5/20 | 0.85 |
| ▸ | NPC1 | O15118 | 4/20 | 0.85 |
| ▸ | CCR6 | P51684 | 2/20 | 0.85 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608716 | 0.92 | KMT2A (1.00) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL1542189 | 0.91 | KMT2A (0.83) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL2153850 | 0.91 | MAPT (1.00) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL30868633 | 0.89 | KMT2A (0.80) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL1542152 | 0.89 | KMT2A (0.80) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL12839880 | 0.87 | ALOX12 (0.81) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL2153339 | 0.85 | KDM4E (0.74) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL608048 | 0.85 | KDM4E (1.00) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL1814003 | 0.84 | ADAMTS5 (1.00) | MAPTKMT2AHTTKDM4EMEN1 | |
| SCHEMBL2153908 | 0.84 | HTT (0.72) | MAPTKMT2AHTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | SIERRA SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | MAPT 4328/4885KMT2A 4294/4885HTT 2106/4885 |
| US-11701374-B1 | 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression | TERT, TERF2, RNGTT | MAPT 2505/4885KMT2A 280/4885HTT 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.