SCHEMBL215378

SCHEMBL215378

Cc1ccccc1C1=[C]CC=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
NISCH Q9Y2I1 1/20 0.34
HTR7 P34969 1/20 0.33
PLA2G7 Q13093 1/20 0.32
GAA P10253 1/20 0.32
IDO1 P14902 1/20 0.32
METAP2 P50579 1/20 0.32
GALR1 P47211 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2971380 0.85 TRPA1 (0.33) SMN1; SMN2TSHR
SCHEMBL2971131 0.76 NISCH (0.34) NPC1RAB9ASMN1; SMN2NISCHIDO1
SCHEMBL9343722 0.76 CA1 (0.36) TSHRHPGDCA12CA1CA2
SCHEMBL9345129 0.76 CSNK2A2 (0.37) NPC1RAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL219035 0.73 NISCH (0.38) NPC1RAB9ASMN1; SMN2TSHRNISCH
SCHEMBL2972485 0.72 TRPA1 (0.31) TSHRALDH1A1
SCHEMBL816149 0.69 PNMT (0.44) NPC1RAB9ASMN1; SMN2HTR7ALDH1A1
SCHEMBL2970250 0.69 BCAT1 (0.31)
SCHEMBL2047337 0.67 ACHE (0.35) ACHENISCH
SCHEMBL197690 0.67 ACHE (0.64) NPC1RAB9ASMN1; SMN2CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-10604604-B2 Multimodal polyolefin resin, and molded body manufactured therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2020-03-31 US disclosed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-3239196-B1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME DAELIM IND CO LTD (KR) 2019-08-28 EP disclosed
US-20180305481-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM DL CHEMICAL CO., LTD. (KR) 2018-10-25 US disclosed
EP-3369752-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM Daelim Industrial Co., Ltd. (KR) 2018-09-05 EP disclosed
CN-108350113-A Multimodal polyolefin resin and molded body produced therefrom 大林产业株式会社 2018-07-31 CN disclosed
US-9975977-B2 Multimodal polyolefin resin having high melt strength and molded product prepared with the same DAELIM INDUSTRIAL CO., LTD. (KR) 2018-05-22 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
CN-107365397-A Multimodal polyolefin resin and shaped article prepared therefrom with high molten intensity 大林产业株式会社 2017-11-21 CN disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-7214747-B2 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-08 US disclosed
US-7214746-B2 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-08 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed
US-7166684-B2 Transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2007-01-23 US disclosed
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2006-07-27 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
US-5279999-A Catalyst composition SHELL OIL COMPANY (US) 1994-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 NPC1 3144/4885RAB9A 4275/4885SMN1; SMN2 2136/4885
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization PYM1, ZNF207, POLL NPC1 4195/4885RAB9A 3440/4885SMN1; SMN2 4049/4885
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin PCLAF, ZKSCAN2, POF1B NPC1 2771/4885RAB9A 3956/4885SMN1; SMN2 4225/4885
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 NPC1 2433/4885RAB9A 3256/4885SMN1; SMN2 4055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.