Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606796 | 0.95 | HTT (0.67) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL482310 | 0.92 | PKM (0.58) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16221627 | 0.90 | HTT (0.61) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL23075718 | 0.85 | HTR6 (0.54) | GAAHTTSMN1; SMN2PKMELANE | |
| SCHEMBL19632244 | 0.84 | HTT (0.54) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL317934 | 0.83 | ACHE (0.50) | TDP1BCHEACHEMAPTMEN1 | |
| SCHEMBL16281927 | 0.83 | ALDH1A1 (0.50) | GAAPKMELANEBCHEACHE | |
| SCHEMBL10988447 | 0.83 | BCHE (0.66) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL419122 | 0.83 | ELANE (0.65) | GAAHTTSMN1; SMN2PKMELANE | |
| SCHEMBL12606789 | 0.82 | GAA (0.53) | GAAHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10465046-B2 | Polyarylether ketone imide adhesives | THE BOEING COMPANY (US) | 2019-11-05 | — | — | US | disclosed |