Guaiacol Carbonate

Guaiacol Carbonate

SCHEMBL21541

COc1ccccc1OC(=O)Oc1ccccc1OC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA12 O43570 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA4 P22748 1/20 0.62
POLB P06746 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HTT P42858 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MTNR1A P48039 2/20 0.50
MTNR1B P49286 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiacol Carbonate SCHEMBL29750682 1.00 CA1 (0.62) CA1CA2CA12CA7CA9
Guaiacol Carbonate SCHEMBL5176484 0.92 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL982771 0.91 HSD17B10 (0.63) CA1CA2CA12CA7CA9
SCHEMBL7882509 0.90 HPGD (0.54) CA1CA2CA12CA7CA9
SCHEMBL26622055 0.87 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL8579858 0.86 CA1 (0.62) CA1CA2CA12CA7CA9
SCHEMBL30909436 0.86 CA1 (0.62) CA1CA2CA12CA7CA9
SCHEMBL9244260 0.85 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL6890110 0.84 MAPT (0.51) CA1CA2CA12CA7CA9
SCHEMBL6890105 0.84 CA12 (0.48) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638550-A1 PROCESS FOR THE PRODUCTION OF A CARBONATE POLYESTER (CO)POLYMER Avantium Knowledge Centre B.V. (NL) 2025-10-29 EP claimed
WO-2024133192-A1 PROCESS FOR THE PRODUCTION OF A CARBONATE POLYESTER (CO)POLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2024-06-27 WO claimed
CN-117024846-A Method for degrading polycarbonate by using phenol catalyst 中国科学院青岛生物能源与过程研究所 2023-11-10 CN claimed
CN-109988296-B Process for producing polycarbonate polyol and polycarbonate polyol composition 财团法人工业技术研究院 2021-09-10 CN claimed
WO-2021054927-A2 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2021-03-25 WO claimed
CN-112225647-A Method for synthesizing 5-bromo-2-methoxyphenol 河南中医药大学 2021-01-15 CN claimed
US-10689488-B2 Method for preparing polycarbonate polyol and composition comprising the polycarbonate polyol INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-06-23 US claimed
CN-111138406-A Sulfonium sulfonate photo-acid generator synthesized from guaiol and synthesis method thereof 上海博栋化学科技有限公司 2020-05-12 CN claimed
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2020-02-13 US claimed
US-20190202981-A1 METHOD FOR PREPARING POLYCARBONATE POLYOL AND COMPOSITION COMPRISING THE POLYCARBONATE POLYOL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-07-04 US claimed
CN-103189108-A Theobromine in combination with an expectorant or a mucolytic for use in therapy BIOCOPEA LTD 2013-07-03 CN claimed
EP-2608847-A1 THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY Biocopea Limited (GB) 2013-07-03 EP claimed
WO-2013004999-A1 DRUG COMBINATIONS AND USES IN TREATING A COUGHING CONDITION BIOCOPEA LIMITED (GB) 2013-01-10 WO claimed
WO-2012025761-A1 THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY BIOCOPEA LIMITED (GB) 2012-03-01 WO claimed
US-8022241-B2 Processes for producing carbonic ester and producing polycarbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2011-09-20 US claimed
US-20100004479-A1 PROCESSES FOR PRODUCING CARBONIC ESTER AND PRODUCING POLYCARBONATE NATIONAL INSTIT. OF ADVANCE INDUST SCIENCE AND TECH (JP) 2010-01-07 US claimed
US-7182796-B2 Odorant for fuel gas SODA AROMATIC CO., LTD. (JP) 2007-02-27 US claimed
US-20050234259-A1 Processes for producing carbonic ester and producing polycarbonate NATIONAL INSTIT OF ADVANCE INDUST SCIENCE AND TECH (JP) 2005-10-20 US claimed
US-20050020479-A1 Odorant for fuel gas SODA AROMATIC CO., LTD. (JP) 2005-01-27 US claimed
EP-1457547-A1 ODORANT FOR FUEL GAS SODA AROMATIC COMPANY, LIMITED (JP) 2004-09-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS GSTK1, GSTO1, GSTM2 CA1 725/4885CA2 2428/4885CA12 1970/4885
US-20100004479-A1 PROCESSES FOR PRODUCING CARBONIC ESTER AND PRODUCING POLYCARBONATE HPD, PAH, PCCA CA1 418/4885CA2 238/4885CA12 171/4885
US-20050234259-A1 Processes for producing carbonic ester and producing polycarbonate HPD, PAH, PCCA CA1 418/4885CA2 238/4885CA12 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.