Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240558 | 0.84 | GBA1 (0.37) | GBA1ALDH1A1HTTNPC1MAPT | |
| SCHEMBL17696428 | 0.79 | ALOX15 (0.33) | GBA1ALDH1A1HTTSMN1; SMN2ALOX15 | |
| SCHEMBL20241988 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HTTNPC1SMN1; SMN2MAPT | |
| SCHEMBL23570033 | 0.78 | PGK1 (0.35) | SMN1; SMN2KDM4EALOX15KMT2ATRPM5 | |
| SCHEMBL20797650 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2KDM4EMAPT | |
| SCHEMBL17693920 | 0.75 | CRHR1 (0.34) | ALDH1A1HTTSMN1; SMN2ALOX15TERT | |
| SCHEMBL24007351 | 0.75 | HTT (0.34) | ALDH1A1HTTNPC1KMT2A | |
| SCHEMBL13651163 | 0.74 | GBA1 (0.42) | GBA1ALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL24696647 | 0.73 | APLNR (0.43) | ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL30127393 | 0.73 | APLNR (0.43) | ALDH1A1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564230-A1 | SUBSTITUTED GUANIDINE COMPOUND | UBE Industries, Ltd. (JP) | 2019-11-06 | — | — | EP | disclosed |