Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548879 | 0.88 | HTT (0.45) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL20356656 | 0.83 | P2RX7 (0.40) | HTTLMNAALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL21526059 | 0.82 | P2RX7 (0.40) | HTTLMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL21548886 | 0.81 | GRM4 (0.35) | SMN1; SMN2ALDH1A1P2RX7MEN1KMT2A | |
| SCHEMBL21548857 | 0.79 | KMT2A (0.34) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL21548814 | 0.78 | LMNA (0.39) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL20356511 | 0.75 | ALDH1A1 (0.46) | HTTLMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL20356758 | 0.73 | ALDH1A1 (0.41) | HTTLMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL21548877 | 0.72 | ALDH1A1 (0.43) | HTTSMN1; SMN2ALDH1A1SLC6A4PKM | |
| SCHEMBL20356509 | 0.68 | PTGER1 (0.39) | ALDH1A1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |