Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550119 | 0.76 | APLNR (0.35) | APLNRFDFT1 | |
| SCHEMBL20157925 | 0.70 | ALDH1A1 (0.36) | APLNRDPP4DPP7 | |
| SCHEMBL21550145 | 0.68 | MDM2 (0.33) | APLNRDPP4DPP7FDFT1 | |
| SCHEMBL21550256 | 0.68 | RORC (0.41) | — | |
| SCHEMBL21564743 | 0.67 | USP14 (0.33) | — | |
| SCHEMBL21550018 | 0.66 | MDM2 (0.49) | — | |
| SCHEMBL21550122 | 0.66 | ALDH1A1 (0.41) | APLNRFDFT1 | |
| SCHEMBL21564721 | 0.65 | MDM2 (0.30) | — | |
| SCHEMBL28473298 | 0.65 | MDM2 (0.46) | — | |
| SCHEMBL28476113 | 0.64 | MDM2 (0.39) | APLNRDPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214399-A1 | BENZO- SEVEN-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | 罗欣药业(上海)有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |