Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551990 | 0.82 | LMNA (0.54) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL21551981 | 0.80 | LMNA (0.52) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL21551941 | 0.80 | HDAC6 (0.62) | HDAC2HDAC8HDAC6MAPTTSHR | |
| SCHEMBL178534 | 0.78 | KMT2A (0.71) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL12760681 | 0.78 | MAPT (0.64) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL16227646 | 0.77 | ALDH1A1 (0.69) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL21551964 | 0.77 | TSHR (0.54) | MAPTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL19226707 | 0.76 | SMN1; SMN2 (0.92) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL21551954 | 0.75 | TSHR (0.69) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL12074931 | 0.75 | LMNA (0.92) | HDAC2HDAC8HDAC6MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |