Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551989 | 0.91 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL21551944 | 0.89 | TSHR (0.59) | LMNAALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL21551981 | 0.88 | LMNA (0.52) | LMNAHDAC2HDAC8HDAC6HTT | |
| SCHEMBL21551985 | 0.82 | CD274 (0.67) | LMNAHTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21551957 | 0.82 | HDAC2 (0.59) | LMNAHDAC2HDAC8HDAC6HTT | |
| SCHEMBL21552083 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTRAD52MEN1KMT2A | |
| SCHEMBL21551982 | 0.77 | ALDH1A1 (0.59) | LMNAALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL21568003 | 0.77 | HPGD (0.55) | LMNAHTTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10756632 | 0.77 | TMEM97 (0.72) | LMNAHTTALDH1A1GAAMAPT | |
| Methane SCHEMBL21551969 | 0.76 | HPGD (0.54) | LMNAHTTALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |