Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552083 | 0.91 | ALDH1A1 (0.55) | DRD2DRD3RAD52MEN1KMT2A | |
| SCHEMBL21551982 | 0.89 | ALDH1A1 (0.59) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL21551990 | 0.88 | LMNA (0.54) | LMNAHDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL21568402 | 0.87 | ALDH1A1 (0.52) | LMNAHDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL21552169 | 0.85 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21568404 | 0.84 | ALDH1A1 (0.49) | LMNAHDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL21552245 | 0.83 | CD274 (0.68) | LMNAKMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL21551957 | 0.80 | HDAC2 (0.59) | LMNAHDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL21551989 | 0.78 | ALDH1A1 (0.54) | LMNADRD2DRD3MEN1KMT2A | |
| SCHEMBL21551949 | 0.78 | SMN1; SMN2 (0.58) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |