Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551983 | 0.94 | CYP1A2 (0.54) | TSHRMAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21551954 | 0.90 | TSHR (0.69) | TSHRLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL21551941 | 0.84 | HDAC6 (0.62) | TSHRMAPTDRD2DRD3NAMPT | |
| SCHEMBL21551975 | 0.84 | TSHR (0.59) | TSHRLMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL21552083 | 0.82 | ALDH1A1 (0.55) | MAPTRECQLKMT2AALDH1A1DRD2 | |
| SCHEMBL14006003 | 0.79 | TSHR (0.70) | TSHRLMNAMAPTRECQLALDH1A1 | |
| SCHEMBL21551989 | 0.77 | ALDH1A1 (0.54) | LMNAMAPTRECQLKMT2AALDH1A1 | |
| SCHEMBL21551957 | 0.77 | HDAC2 (0.59) | TSHRLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL21551953 | 0.76 | CYP1A2 (0.50) | LMNAMAPTKMT2AALDH1A1GAA | |
| SCHEMBL5481939 | 0.76 | TSHR (0.66) | TSHRLMNAMAPTRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |