Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557614 | 0.93 | F2 (0.44) | ABL1GSK3BDYRK1ABCRFAAH | |
| SCHEMBL21557499 | 0.85 | MAP4K4 (0.50) | ABL1GSK3BDYRK1AFAAHKCNH2 | |
| SCHEMBL21557568 | 0.79 | ABL1 (0.42) | ABL1GSK3BDYRK1ABCRAXL | |
| SCHEMBL21557622 | 0.78 | F2 (0.47) | ABL1GSK3BDYRK1AFAAHKAT6A | |
| SCHEMBL2813791 | 0.77 | AKR1C3 (0.42) | ABL1BCRPDE5AMAP4K4 | |
| SCHEMBL12891743 | 0.77 | DRD2 (0.41) | ABL1GSK3BDYRK1AFAAHKCNH2 | |
| SCHEMBL26820010 | 0.77 | DRD2 (0.41) | ABL1GSK3BDYRK1AFAAHKCNH2 | |
| SCHEMBL12891748 | 0.77 | DRD2 (0.41) | ABL1GSK3BDYRK1AFAAHKCNH2 | |
| SCHEMBL21557578 | 0.77 | FAAH (0.54) | ABL1GSK3BDYRK1AFAAHAXL | |
| SCHEMBL1153666 | 0.74 | PIN1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | MEDSHINE DISCOVERY INC. (CN) | 2020-05-12 | — | — | US | disclosed |
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | TSLP, TK2, TK1 | ABL1 881/4885GSK3B 1337/4885DYRK1A 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.