Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 13/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591699 | 0.76 | MTNR1B (0.51) | MTNR1BMTNR1ANNMT | |
| SCHEMBL21591748 | 0.75 | MTNR1B (0.50) | MTNR1BMTNR1ANNMT | |
| SCHEMBL23555513 | 0.75 | L3MBTL1 (0.39) | NNMT | |
| SCHEMBL21591711 | 0.75 | MTNR1A (0.53) | MTNR1BMTNR1ANNMT | |
| SCHEMBL23555514 | 0.74 | NNMT (0.50) | NNMT | |
| SCHEMBL31088740 | 0.72 | TUBB4A (0.33) | — | |
| SCHEMBL31089176 | 0.71 | TUBB4A (0.31) | — | |
| SCHEMBL31089280 | 0.69 | MAPT (0.40) | — | |
| SCHEMBL31089007 | 0.68 | ACVR2A (0.33) | — | |
| SCHEMBL4315975 | 0.65 | RECQL (0.43) | MTNR1BMTNR1ANNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807270-A1 | NOVEL HETEROARYL HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238616-A1 | NOVEL HETEROARYL HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2019-12-19 | — | — | WO | disclosed |