Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.33 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323144 | 0.70 | CYP1A2 (0.33) | IDO1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2159967 | 0.70 | NOTUM (0.32) | — | |
| SCHEMBL3096746 | 0.70 | APAF1 (0.33) | IDO1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1091565 | 0.65 | GPR84 (0.35) | LMNATSHR | |
| SCHEMBL15156660 | 0.65 | S100A4 (0.38) | SMN1; SMN2TP53LMNAMAPTHTT | |
| SCHEMBL816040 | 0.65 | ALDH1A1 (0.31) | IDO1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5737227 | 0.65 | MEN1 (0.33) | CYP2A6LMNAALDH1A1TDP1 | |
| SCHEMBL8078829 | 0.64 | ALDH1A1 (0.36) | SMN1; SMN2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL20585044 | 0.64 | MAPT (0.43) | IDO1DNMT1DNMT3LDNMT3ANPC1 | |
| SCHEMBL17321809 | 0.63 | IDO1 (0.40) | IDO1DNMT1DNMT3LDNMT3ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194314-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-05-22 | — | — | CN | disclosed |
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110166020-A1 | Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | ABAT, OAT, TYR | IDO1 83/4885DNMT1 2389/4885DNMT3L 2477/4885 |
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | OAT, ABAT, TYR | IDO1 84/4885DNMT1 2079/4885DNMT3L 2634/4885 |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | IDO1 10/4885DNMT1 3984/4885DNMT3L 2046/4885 |
| US-20110166020-A1 | Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds | COX4I1, NISCH, TPMT | IDO1 114/4885DNMT1 899/4885DNMT3L 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.