SCHEMBL816040

SCHEMBL816040

CC(C)(C)C1=C[N]c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
MCL1 Q07820 1/20 0.31
ATM Q13315 1/20 0.31
IDO1 P14902 1/20 0.31
NPC1 O15118 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7835401 0.75 TSHR (0.34) ALDH1A1IDO1
SCHEMBL323144 0.70 CYP1A2 (0.33) ALDH1A1MAPTATMIDO1NPC1
SCHEMBL3096746 0.65 APAF1 (0.33) ALDH1A1MAPTMCL1IDO1NPC1
SCHEMBL2159745 0.65 IDO1 (0.33) ALDH1A1MAPTIDO1NPC1RAB9A
SCHEMBL9754870 0.61 ALDH1A1 (0.39) ALDH1A1MAPT
SCHEMBL5737227 0.61 MEN1 (0.33) ALDH1A1MEN1KMT2A
SCHEMBL1091565 0.61 GPR84 (0.35)
SCHEMBL8078829 0.60 ALDH1A1 (0.36) ALDH1A1MAPTL3MBTL1
SCHEMBL20585044 0.60 MAPT (0.43) ALDH1A1MAPTMCL1IDO1NPC1
SCHEMBL5473842 0.59 ALDH1A1 (0.32) ALDH1A1MAPTATMNPC1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144791-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-04 US claimed
US-20170158790-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2017-06-08 US claimed
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP disclosed
CN-113201084-A Molecular weight control of polyolefins using halogenated bisphenylphenoxy catalysts 陶氏环球技术有限责任公司 2021-08-03 CN disclosed
US-10836697-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-17 US disclosed
EP-2797963-B1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-03 EP disclosed
US-20190112250-A1 PROCESS FOR THE PREPARATION OF LIGHTLY-BRANCHED HYDROPHOBES AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-18 US disclosed
US-10196336-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-05 US disclosed
US-10144791-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-04 US disclosed
EP-2986586-B1 PROCESS FOR THE PREPARATION OF A LIGHTLY-BRANCHED HYDROPHOBE AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-08 EP disclosed
US-9963648-B2 Process for the preparation of branched polyolefins for lubricant applications DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-08 US disclosed
WO-2014209711-A1 PROCESS FOR THE PREPARATION OF LIGHTLY-BRANCHED HYDROPHOBES AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO disclosed
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-04 US disclosed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US disclosed
EP-2797963-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID Dow Global Technologies LLC (US) 2014-11-05 EP disclosed
US-20140163186-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-12 US disclosed
US-8609794-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES, LLC. (US) 2013-12-17 US disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10836697-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof ERG28, CLTB, CHN2 ALDH1A1 3530/4885MAPT 1636/4885MCL1 3143/4885
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS EEF1D, EPN1, ELOC ALDH1A1 4014/4885MAPT 863/4885MCL1 2745/4885
US-10196336-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof ERG28, CLTB, CHN2 ALDH1A1 3530/4885MAPT 1636/4885MCL1 3143/4885
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 ALDH1A1 2392/4885MAPT 1699/4885MCL1 3421/4885
US-20190112250-A1 PROCESS FOR THE PREPARATION OF LIGHTLY-BRANCHED HYDROPHOBES AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF ERG28, CLTB, CHN2 ALDH1A1 3641/4885MAPT 1522/4885MCL1 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.