Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600730 | 0.85 | MMP13 (0.42) | ALDH1A1PKMPKLR | |
| SCHEMBL21600740 | 0.83 | MMP2 (0.37) | ALDH1A1GRM2HTR6NFE2L2 | |
| SCHEMBL21600709 | 0.82 | PSIP1 (0.36) | ALDH1A1PKMCYP19A1 | |
| SCHEMBL21600726 | 0.81 | TSHR (0.51) | ALDH1A1PKMPOLBL3MBTL1 | |
| SCHEMBL21600743 | 0.76 | CYP3A4 (0.37) | ALDH1A1 | |
| SCHEMBL21600727 | 0.76 | NAPRT (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL24246845 | 0.76 | PTGS2 (0.36) | ALDH1A1POLB | |
| SCHEMBL21600737 | 0.75 | PSEN1 (0.40) | ALDH1A1POLB | |
| SCHEMBL24246859 | 0.75 | GAA (0.38) | ALDH1A1GRM2HTR6L3MBTL1CYP19A1 | |
| SCHEMBL21600717 | 0.75 | L3MBTL1 (0.38) | ALDH1A1GRM2FFAR4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | FUJIAN HAIXI PHARMACEUTICALS CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | FUJIAN HAIXI PHARMACEUTICALS CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| EP-3798211-A1 | COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG | Fujian Haixi Pharmaceuticals Co., Ltd (CN) | 2021-03-31 | — | — | EP | disclosed |
| WO-2019242692-A1 | COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG | 福建海西新药创制有限公司 | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | CYP3A43, POR, CYP2C19 | ALDH1A1 1227/4885PKM 32/4885PKLR 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.