SCHEMBL216031

SCHEMBL216031

C=CCC[SiH](OC(C)=O)OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 3/20 0.34
USP2 O75604 2/20 0.34
CYP3A4 P08684 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
RECQL P46063 1/20 0.34
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ABCC4 O15439 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951108 0.88 ALDH1A1 (0.40) ALDH1A1LMNAMAPTUSP2CYP3A4
SCHEMBL71978 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL8460915 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13089624 0.74 ALDH1A1 (0.33) ALDH1A1LMNA
SCHEMBL5395147 0.72 TSHR (0.48) ALDH1A1CYP3A4SMN1; SMN2HPGD
SCHEMBL705156 0.72 ALDH1A1 (0.38) ALDH1A1LMNA
SCHEMBL7640843 0.71 KDM4E (0.37) ALDH1A1LMNAMAPTCYP3A4SMN1; SMN2
SCHEMBL2579458 0.71 TSHR (0.44) ALDH1A1LMNACYP3A4SMN1; SMN2HPGD
SCHEMBL21294328 0.71 LMNA (0.33) ALDH1A1LMNAMAPTUSP2CYP3A4
SCHEMBL5390200 0.70 ALDH1A1 (0.31) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527870-B2 Organosiloxane compositions DOW CORNING CORPORATION (US) 2009-05-05 US claimed
EP-1620491-B1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2007-04-25 EP claimed
US-20060194067-A1 Organosiloxane compositions DOW SILICONES CORPORATION 2006-08-31 US claimed
EP-1620491-A1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2006-02-01 EP claimed
WO-2004094503-A1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2004-11-04 WO claimed
EP-0477765-A2 Thermoplastic, coupled barrier composites THE B.F. GOODRICH COMPANY (US) 1992-04-01 EP claimed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
EP-4715465-A1 MULTILAYER BODY, METHOD FOR PRODUCING MULTILAYER BODY, AND PHOTOSENSITIVE SURFACE MODIFIER Nissan Chemical Corporation (JP) 2026-03-25 EP disclosed
US-12585188-B2 Composition for forming resist underlying film NISSAN CHEMICAL CORPORATION (JP) 2026-03-24 US disclosed
US-12552905-B2 Additive stabilization DOW SILICONES CORPORATION (US) 2026-02-17 US disclosed
EP-3604439-B1 RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORP (JP) 2026-01-14 EP disclosed
EP-4679175-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM Nissan Chemical Corporation (JP) 2026-01-14 EP disclosed
US-20250377596-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-12-11 US disclosed
EP-0349855-A2 Molded article of metathesis polymerized polymer containing fillers and process for its preparation HERCULES INCORPORATED (US) 1990-01-10 EP disclosed
US-4749803-A Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1988-06-07 US disclosed
US-4720534-A NCO-terminated compounds from adducts of mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1988-01-19 US disclosed
EP-0231514-A2 Compositions based on resins having silicon atoms attached to hydrolyzable groups derived from vinyl silanes and mercaptofunctional compounds PPG INDUSTRIES, INC. (US) 1987-08-12 EP disclosed
EP-0229390-A2 Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1987-07-22 EP disclosed
US-4652610-A FLEXIBLE COATINGS; AUTOMOBILE PAINTS PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
US-4652664-A Addition products prepared from mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 ALDH1A1 3642/4885LMNA 474/4885MAPT 965/4885
US-12585188-B2 Composition for forming resist underlying film SRR, SMC1A, ASH2L ALDH1A1 1320/4885LMNA 625/4885MAPT 4790/4885
US-12552905-B2 Additive stabilization RCC1, SCO2, DDT ALDH1A1 334/4885LMNA 761/4885MAPT 2381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.