Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18983290 | 0.81 | MTNR1B (0.57) | ALDH1A1MTNR1BEPHX2MGLLMMP1 | |
| SCHEMBL3856804 | 0.79 | ALDH1A1 (0.52) | ALDH1A1EPHX2SMN1; SMN2STSMEN1 | |
| SCHEMBL21608115 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MGLLKDM4ESMN1; SMN2VEGFA | |
| SCHEMBL23925168 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MTNR1BEPHX2MGLLMMP1 | |
| SCHEMBL10039879 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2VEGFAEGLN1LMNA | |
| SCHEMBL21607887 | 0.74 | POLB (0.47) | ALDH1A1KDM4ETDP1VEGFAEGLN1 | |
| SCHEMBL17515218 | 0.74 | DRD2 (0.57) | KDM4ESMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL21361667 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MGLLKDM4EGAATDP1 | |
| SCHEMBL23924943 | 0.73 | MGLL (0.46) | ALDH1A1MTNR1BEPHX2MGLLMMP1 | |
| SCHEMBL892981 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2VEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |