SCHEMBL2160768

SCHEMBL2160768

N[C@H](CC(CC(Cl)(Cl)Cl)C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 6/20 0.57
SLC1A2 P43004 7/20 0.55
SLC1A3 P43003 5/20 0.55
GRIK1 P39086 10/20 0.53
GRIK2 Q13002 10/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2160766 1.00 SLC1A1 (0.57) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL5295103 0.80 PTGS1 (0.46) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL11381471 0.79 CHRM1 (0.38) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL4477147 0.73 SLC1A1 (1.00) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL5293587 0.73 SLC1A1 (0.67) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL7103579 0.73 SLC1A1 (1.00) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL27784432 0.72 SLC1A2 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL27817249 0.72 SLC1A2 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL27806425 0.72 SLC1A2 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL13621431 0.71 SLC1A1 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-03-10 US disclosed
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-07-29 US disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP disclosed
US-10471020-B2 Nanoparticles with protected interiors, and methods of use thereof UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2019-11-12 US disclosed
US-20180078510-A1 NANOPARTICLES WITH PROTECTED INTERIORS, AND METHODS OF USE THEREOF UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2018-03-22 US disclosed
US-9415019-B2 Nanocapsules with a polymer shell UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2016-08-16 US disclosed
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2015-04-09 US disclosed
US-20140023703-A1 NANOCAPSULES WITH A POLYMER SHELL UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2014-01-23 US disclosed
EP-2664324-A1 NANOCAPSULES WITH A POLYMER SHELL Universidade De Santiago De Compostela (ES) 2013-11-20 EP disclosed
US-20110182813-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2011-07-28 US disclosed
EP-2042538-A1 Amphiphilic copolymers and compositions containing such polymers Nirvana's Tree House (NL) 2009-04-01 EP disclosed
WO-2009037313-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2009-03-26 WO disclosed
US-7005123-B1 Functional poly-α-amino-acid derivatives useful for the modification of biologically active materials and their application UNIVERSITEIT GENT (BE) 2006-02-28 US disclosed
EP-1189971-B1 FUNCTIONAL POLY-ALPHA-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION UNIV GENT (BE) 2005-03-09 EP disclosed
US-6590061-B1 Synthetic polypeptide or peptides having narrow molecular weight distribution used as telechelic polymers for synthesis of block or graft copolymers INSTITUTE OF MACROMOLECULAR CHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-07-08 US disclosed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP disclosed
EP-1189971-A2 FUNCTIONAL POLY-ALPHA-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION UNIVERSITEIT GENT (BE) 2002-03-27 EP disclosed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP disclosed
WO-2000078791-A2 FUNCTIONAL POLY-α-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION UNIVERSITEIT GENT (BE) 2000-12-28 WO disclosed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN SLC1A1 254/4885SLC1A2 464/4885SLC1A3 248/4885
US-20110182813-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS GLUL, ASNS, ARGLU1 SLC1A1 87/4885SLC1A2 84/4885SLC1A3 78/4885
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS GLUL, ASNS, ARGLU1 SLC1A1 87/4885SLC1A2 84/4885SLC1A3 78/4885
US-20140023703-A1 NANOCAPSULES WITH A POLYMER SHELL PGA5, IL15, CD44 SLC1A1 4286/4885SLC1A2 4279/4885SLC1A3 4257/4885
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN SLC1A1 254/4885SLC1A2 464/4885SLC1A3 248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.