Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 3/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26814530 | 0.77 | HCAR3 (0.38) | DTYMKMAPTMEN1KMT2AHCAR3 | |
| SCHEMBL26814567 | 0.75 | FABP4 (0.41) | PDE5AMAPTMEN1KMT2AHCAR3 | |
| SCHEMBL26814541 | 0.75 | HCAR3 (0.40) | DTYMKPDE5AMAPTMEN1KMT2A | |
| SCHEMBL29686047 | 0.74 | GPR119 (0.54) | MAPTALDH1A1 | |
| SCHEMBL21612824 | 0.74 | GPR119 (0.54) | MAPTALDH1A1 | |
| SCHEMBL31145708 | 0.73 | DTYMK (0.40) | DTYMKPDE5AMEN1KMT2AHCAR3 | |
| SCHEMBL31510002 | 0.72 | DTYMK (0.39) | DTYMKPDE5AMEN1KMT2AHCAR3 | |
| SCHEMBL16649234 | 0.71 | PKM (0.54) | DTYMKMAPTMEN1KMT2AGAA | |
| SCHEMBL4230982 | 0.71 | HCAR3 (0.41) | DTYMKPDE5AMAPTMEN1KMT2A | |
| SCHEMBL21616255 | 0.71 | PDE5A (0.37) | PDE5AMAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009156-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVE | 第一三共株式会社 | 2020-01-09 | — | — | WO | disclosed |