Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898313 | 0.87 | PTPN7 (0.54) | HPGDALDH1A1ALOX15CYP1A2CYP3A4 | |
| SCHEMBL899104 | 0.86 | PTPN7 (0.53) | HPGDALDH1A1ALOX15CYP1A2CYP3A4 | |
| SCHEMBL899105 | 0.86 | PTPN7 (0.53) | HPGDALDH1A1ALOX15CYP1A2CYP3A4 | |
| SCHEMBL21623925 | 0.85 | HPGD (0.53) | HPGDPOLBLMNAALDH1A1ALOX15 | |
| SCHEMBL29535664 | 0.81 | ALOX15 (0.62) | ALDH1A1ALOX15ALPLGFERPOLA1 | |
| SCHEMBL898314 | 0.81 | ALOX15 (0.62) | ALDH1A1ALOX15ALPLGFERPOLA1 | |
| SCHEMBL14156958 | 0.81 | ESR1 (0.61) | HPGDPOLBLMNAALDH1A1KMT2A | |
| SCHEMBL5065588 | 0.80 | TRPV1 (0.59) | HPGDLMNAALDH1A1ALOX15KDM4E | |
| SCHEMBL28950493 | 0.80 | KLKB1 (0.56) | POLBLMNAALDH1A1ALOX15KMT2A | |
| SCHEMBL29085521 | 0.79 | ALPL (0.49) | HPGDALDH1A1ALOX15ALPLKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| US-20190289886-A1 | SUBSTANCE MIXTURES | SYMRISE AG (DE) | 2019-09-26 | — | — | US | claimed |
| EP-3470464-A1 | LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER | Heraeus Deutschland GmbH & Co KG (DE) | 2019-04-17 | — | — | EP | claimed |
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |
| US-20080317923-A1 | AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | claimed |
| EP-2001448-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | Cadbury Adams USA LLC (US) | 2008-12-17 | — | — | EP | claimed |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-04 | — | — | US | claimed |
| WO-2007089652-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | CADBURY ADAMS USA LLC (US) | 2007-08-09 | — | — | WO | claimed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | claimed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | disclosed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | disclosed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | disclosed |
| EP-3689324-B1 | NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM | SYMRISE AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2008046895-A1 | SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | WO | disclosed |
| EP-1909599-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007107596-A1 | USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS | SYMRISE GMBH & CO. KG (DE) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007089652-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | CADBURY ADAMS USA LLC (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007014879-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | HPGD 428/4885POLB 4200/4885LMNA 4817/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | HPGD 1963/4885POLB 2898/4885LMNA 3005/4885 |
| US-20190289886-A1 | SUBSTANCE MIXTURES | PNN, NISCH, HES1 | HPGD 472/4885POLB 2125/4885LMNA 3744/4885 |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | TAS1R1, TAS2R1, TAS1R2 | HPGD 1055/4885POLB 2273/4885LMNA 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.