Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26237112 | 0.91 | MKNK1 (0.32) | MKNK1MKNK2P4HTMKCNJ1 | |
| SCHEMBL21623939 | 0.90 | CYP1A2 (0.38) | MKNK1MKNK2P4HTMALDH1A1 | |
| SCHEMBL24385685 | 0.87 | PANK3 (0.36) | MKNK1MKNK2P4HTMKCNJ1 | |
| SCHEMBL24240290 | 0.77 | MKNK1 (0.34) | MKNK1MKNK2P4HTMKCNJ1 | |
| SCHEMBL24135122 | 0.76 | KCNJ1 (0.38) | MKNK1MKNK2KCNJ1 | |
| SCHEMBL20168007 | 0.76 | KCNJ1 (0.46) | MKNK1MKNK2P4HTMKCNJ1KDM4E | |
| SCHEMBL17940784 | 0.74 | GRM5 (0.44) | GRM5KDM4EALDH1A1 | |
| SCHEMBL21689081 | 0.72 | LMNA (0.42) | MKNK1MKNK2P4HTMGRM5KDM4E | |
| SCHEMBL19402259 | 0.72 | CYP19A1 (0.41) | MKNK1MKNK2GRM5KDM4EALDH1A1 | |
| SCHEMBL21639359 | 0.72 | NPC1 (0.50) | MKNK1MKNK2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192823-B9 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | SANIONA AS (DK) | 2026-03-18 | — | — | EP | disclosed |
| EP-4192823-B1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | SANIONA AS (DK) | 2025-12-17 | — | — | EP | disclosed |
| EP-4596558-A2 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2025-08-06 | — | — | EP | disclosed |
| EP-4596559-A2 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2025-08-06 | — | — | EP | disclosed |
| CN-112424197-B | Difluoromethyl-phenyltriazoles as modulators of GABA receptors | 勃林格殷格翰国际公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-116888115-A | Difluoromethyl-pyridin-2-yl triazoles | 勃林格殷格翰国际有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230286946-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| US-20230286946-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| US-20230286946-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| EP-4192823-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3971179-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2022-03-23 | — | — | EP | disclosed |
| EP-3950683-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2022-02-09 | — | — | EP | disclosed |
| EP-3950683-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2022-02-09 | — | — | EP | disclosed |
| EP-3823967-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES AS GABA RECEPTOR MODULATORS | Boehringer Ingelheim International GmbH (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| CN-112424197-A | Difluoromethyl-phenyl triazoles as GABA receptor modulators | 勃林格殷格翰国际公司 | 2021-02-26 | — | — | CN | disclosed |
| WO-2020016443-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES AS GABA RECEPTOR MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | GABRA5, GABRB1, GABRA1 | MKNK1 3213/4885MKNK2 2604/4885P4HTM 979/4885 |
| US-20230286946-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | GABRA5, GABRA3, GABRA2 | MKNK1 3089/4885MKNK2 2193/4885P4HTM 1198/4885 |
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | GABRA5, GABRB1, GABRA1 | MKNK1 3228/4885MKNK2 2645/4885P4HTM 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.