SCHEMBL21624629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21624630	1.00	SIGMAR1 (0.45)	SIGMAR1OGARPS6KB1MCHR1ACACB
	SCHEMBL21624756	0.92	SIGMAR1 (0.53)	SIGMAR1OGARPS6KB1MCHR1CCR2
	SCHEMBL21624755	0.92	SIGMAR1 (0.53)	SIGMAR1OGARPS6KB1MCHR1CCR2
	SCHEMBL21624714	0.90	SIGMAR1 (0.46)	SIGMAR1RPS6KB1ACACBCCR2AOC3
	SCHEMBL21624725	0.90	ME3 (0.50)	SIGMAR1RPS6KB1MCHR1ACACBCCR2
	SCHEMBL21624710	0.90	SIGMAR1 (0.46)	SIGMAR1RPS6KB1ACACBCCR2AOC3
	SCHEMBL21624722	0.90	ME3 (0.50)	SIGMAR1RPS6KB1MCHR1ACACBCCR2
	SCHEMBL21624743	0.90	SIGMAR1 (0.48)	SIGMAR1OGARPS6KB1MCHR1CCR2
	SCHEMBL21625643	0.89	CCR2 (0.47)	SIGMAR1RPS6KB1MCHR1ACACBCCR2
	SCHEMBL22499968	0.89	RPS6KB1 (0.46)	SIGMAR1OGARPS6KB1PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.