SCHEMBL21625640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21625641	1.00	CCR2 (0.44)	CCR2KCNH2S100A4CYP3A4CYP2D6
	SCHEMBL21624716	0.94	SIGMAR1 (0.45)	CCR2KCNH2CYP3A4CYP2D6CYP2C9
	SCHEMBL21624719	0.94	SIGMAR1 (0.45)	CCR2KCNH2CYP3A4CYP2D6CYP2C9
	SCHEMBL21625663	0.87	ME3 (0.46)	CCR2KCNH2S100A4CYP3A4CYP2D6
	SCHEMBL21625664	0.87	ME3 (0.46)	CCR2KCNH2S100A4CYP3A4CYP2D6
	SCHEMBL21624756	0.86	SIGMAR1 (0.53)	CCR2SIGMAR1GRIN2BAOC3
	SCHEMBL21624755	0.86	SIGMAR1 (0.53)	CCR2SIGMAR1GRIN2BAOC3
	SCHEMBL21624722	0.85	ME3 (0.50)	CCR2SIGMAR1GRIN2BAOC3
	SCHEMBL21624725	0.85	ME3 (0.50)	CCR2SIGMAR1GRIN2BAOC3
	SCHEMBL21624710	0.85	SIGMAR1 (0.46)	CCR2SIGMAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.