SCHEMBL21628422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628863	0.93	MAPT (0.41)	IGFBP3MAPTKDM4ECA12CA1
	SCHEMBL21628575	0.92	MAPT (0.40)	IGFBP3MAPTKDM4ECA12CA1
	SCHEMBL21628636	0.91	MAPT (0.42)	IGFBP3MAPTKDM4ECA12CA1
	SCHEMBL21656741	0.90	MAPT (0.49)	IGFBP3MAPTKDM4ECA12CA1
	SCHEMBL19357358	0.88	ALDH1A1 (0.50)	MAPTKDM4ECA12CA1CA2
	SCHEMBL21628770	0.86	ALDH1A1 (0.51)	IGFBP3MAPTKDM4ECA1CA2
	SCHEMBL21628759	0.86	NPC1 (0.47)	MAPTKDM4ECA12CA1CA2
	SCHEMBL21628569	0.85	IGFBP3 (0.48)	IGFBP3MAPTKDM4ECA12CA1
	SCHEMBL21656853	0.85	CA12 (0.50)	MAPTCA12CA1CA2CA7
	SCHEMBL21628653	0.84	CA12 (0.47)	MAPTKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.