SCHEMBL21628759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19357358	0.90	ALDH1A1 (0.50)	MAPTCA12CA1CA2CA7
	SCHEMBL21628854	0.89	ALDH1A1 (0.52)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21656741	0.88	MAPT (0.49)	RAB9AMAPTCA12CA1CA2
	SCHEMBL21628475	0.86	RAB9A (0.63)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628422	0.86	IGFBP3 (0.42)	POLBMAPTCA12CA1CA2
	SCHEMBL21628636	0.86	MAPT (0.42)	POLBMAPTCA12CA1CA2
	SCHEMBL21628416	0.85	PARP10 (0.50)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628569	0.85	IGFBP3 (0.48)	MAPTCA12CA1CA2CA7
	SCHEMBL21628863	0.84	MAPT (0.41)	POLBMAPTCA12CA1CA2
	SCHEMBL21628653	0.84	CA12 (0.47)	MAPTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.