SCHEMBL21628451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21656765	0.89	MMP13 (0.65)	HDAC1HDAC6IGFBP3MMP13MAPT
	SCHEMBL680462	0.87	SCN9A (0.50)	IGFBP3MMP13MAPTMAPK1KCNQ3
	SCHEMBL21628403	0.85	OPRM1 (0.52)	HDAC1HDAC6OPRM1OPRK1HDAC8
	SCHEMBL21628876	0.85	HDAC1 (0.58)	HDAC1HDAC6OPRM1OPRK1MAPT
	SCHEMBL29921049	0.85	HDAC6 (0.49)	HDAC1HDAC6OPRM1OPRK1HDAC8
	SCHEMBL21628789	0.85	HDAC6 (0.49)	HDAC1HDAC6OPRM1OPRK1HDAC8
	SCHEMBL21628782	0.84	TDP1 (0.54)	IGFBP3MMP13MAPTMAPK1LMNA
	SCHEMBL21628442	0.84	MAPK1 (0.61)	IGFBP3MMP13MAPTMAPK1LMNA
	SCHEMBL21628602	0.83	MAPT (0.52)	HDAC1HDAC6IGFBP3OPRM1OPRK1
	SCHEMBL21628730	0.82	PARP10 (0.59)	IGFBP3OPRM1OPRK1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.