SCHEMBL21628482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628424	0.91	VNN1 (0.42)	VNN1LMNAMAPTPTGER4NPC1
	SCHEMBL21628713	0.89	MDH1 (0.48)	VNN1LMNAMAPTNPC1RAB9A
	SCHEMBL21628642	0.89	MAOB (0.48)	LMNAMAPTL3MBTL1PTGER4RAB9A
	SCHEMBL21628478	0.88	MAPT (0.50)	MAPTSMN1; SMN2
	SCHEMBL21628506	0.88	RXRA (0.49)	VNN1MAPTL3MBTL1PTGER4NPC1
	SCHEMBL21656917	0.88	PLK1 (0.49)	VNN1MAPTL3MBTL1PTGER4SMN1; SMN2
	SCHEMBL21628870	0.88	PTGER4 (0.45)	VNN1MAPTL3MBTL1PTGER4PTGER2
	SCHEMBL21628473	0.87	MAPT (0.49)	MAPTSMN1; SMN2
	SCHEMBL21628389	0.87	CHEK2 (0.45)	VNN1MAPTL3MBTL1PTGER4MAOB
	SCHEMBL21628625	0.87	TDP1 (0.46)	LMNAMAPTL3MBTL1PTGER4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.