SCHEMBL21628693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628487	0.91	SLC6A2 (0.49)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628876	0.88	HDAC1 (0.58)	OPRM1OPRK1HDAC1HDAC6HDAC8
	SCHEMBL21628854	0.87	ALDH1A1 (0.52)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628475	0.86	RAB9A (0.63)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628416	0.85	PARP10 (0.50)	NPC1RAB9APOLBCYP2C9OPRM1
	SCHEMBL21628465	0.85	NPC1 (0.58)	NPC1RAB9APOLBCYP2C9HDAC1
	SCHEMBL21628602	0.84	MAPT (0.52)	OPRM1OPRK1HDAC1HDAC6HDAC8
	SCHEMBL21628759	0.83	NPC1 (0.47)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628755	0.83	SLC6A2 (0.51)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21628403	0.83	OPRM1 (0.52)	OPRM1OPRK1HDAC1HDAC6HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.