SCHEMBL21628512

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628767	0.93	ICAM1 (0.44)	OPRM1OPRD1OPRK1GRIN2DGRIN3B
	SCHEMBL21628609	0.92	ICAM1 (0.48)	OPRM1OPRD1OPRK1ICAM1SELE
	SCHEMBL21628454	0.91	ICAM1 (0.49)	OPRM1OPRD1OPRK1ALDH1A1RAB9A
	SCHEMBL21628389	0.90	CHEK2 (0.45)	OPRM1OPRD1OPRK1VNN1HPGDS
	SCHEMBL21628805	0.89	PTGER4 (0.46)	OPRM1OPRD1OPRK1ALDH1A1RAB9A
	SCHEMBL21628424	0.87	VNN1 (0.42)	ALDH1A1RAB9ASENP8SENP7SENP6
	SCHEMBL21628686	0.86	PLK1 (0.51)	OPRM1OPRD1OPRK1ALDH1A1RAB9A
	SCHEMBL21628761	0.86	MAOB (0.46)	ALDH1A1SENP8SENP7SENP6MAOB
	SCHEMBL21628586	0.86	ALDH1A1 (0.41)	SLC6A2ALDH1A1RAB9ASENP8SENP7
	SCHEMBL21628856	0.86	PTGER4 (0.44)	OPRM1OPRD1OPRK1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.