SCHEMBL21628586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628763	0.93	PLA2G4A (0.41)	ALDH1A1SMN1; SMN2HPGDMAPTKMT2A
	SCHEMBL21628577	0.92	PLA2G4A (0.45)	ALDH1A1SMN1; SMN2HPGDPLA2G4ATHRB
	SCHEMBL21628638	0.91	PLA2G4A (0.46)	PLA2G4ATHRB
	SCHEMBL21628376	0.91	SMN1; SMN2 (0.43)	ALDH1A1SMN1; SMN2HPGDMAPTPTGER4
	SCHEMBL21628805	0.87	PTGER4 (0.46)	ALDH1A1SMN1; SMN2SENP8SENP7SENP6
	SCHEMBL21628512	0.86	OPRM1 (0.43)	ALDH1A1SENP8SENP7SENP6RAB9A
	SCHEMBL21628424	0.85	VNN1 (0.42)	ALDH1A1SMN1; SMN2SENP8SENP7SENP6
	SCHEMBL21628703	0.84	SMN1; SMN2 (0.46)	ALDH1A1SMN1; SMN2HPGDRAB9ANPC1
	SCHEMBL21628761	0.84	MAOB (0.46)	ALDH1A1SENP8SENP7SENP6MAPT
	SCHEMBL21628686	0.84	PLK1 (0.51)	ALDH1A1SMN1; SMN2HPGDSENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.