SCHEMBL21628556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628453	0.98	MAPT (0.43)	MAPTALDH1A1SMN1; SMN2MAOBLMNA
	SCHEMBL21628597	0.97	ALDH1A1 (0.45)	MAPTALDH1A1SMN1; SMN2MAOBLMNA
	SCHEMBL21628680	0.97	ALDH1A1 (0.45)	MAPTALDH1A1SMN1; SMN2MAOBLMNA
	SCHEMBL21628869	0.96	MAOB (0.40)	MAPTALDH1A1SMN1; SMN2MAOBLMNA
	SCHEMBL21628393	0.88	ALOX5AP (0.45)	MAPTALDH1A1SMN1; SMN2LMNA
	SCHEMBL21628687	0.86	ALOX5AP (0.43)	MAPTALDH1A1SMN1; SMN2LMNA
	SCHEMBL21628488	0.85	SMN1; SMN2 (0.42)	MAPTALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL21628383	0.85	SMN1; SMN2 (0.42)	MAPTALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL21628405	0.84	FEN1 (0.42)	SMN1; SMN2POLBL3MBTL1
	SCHEMBL21628659	0.84	MAOB (0.52)	MAPTALDH1A1MAOBLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.