SCHEMBL21628763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628577	0.97	PLA2G4A (0.45)	PLA2G4AALDH1A1HPGDSMN1; SMN2LPAR1
	SCHEMBL21628638	0.96	PLA2G4A (0.46)	PLA2G4ATRPV1RARB
	SCHEMBL21628586	0.93	ALDH1A1 (0.41)	PLA2G4AALDH1A1HPGDSMN1; SMN2LMNA
	SCHEMBL21628376	0.89	SMN1; SMN2 (0.43)	ALDH1A1HPGDSMN1; SMN2LMNAMAPT
	SCHEMBL21628425	0.87	RARB (0.48)	PLA2G4AALDH1A1SMN1; SMN2LPAR1LPAR5
	SCHEMBL21628767	0.86	ICAM1 (0.44)	PLA2G4AALDH1A1RARBKDM4EMEN1
	SCHEMBL21628713	0.85	MDH1 (0.48)	ALDH1A1SMN1; SMN2LPAR1LPAR5TRPV1
	SCHEMBL21628665	0.84	SMPD1 (0.47)	ALDH1A1SMN1; SMN2TRPV1NFKB1
	SCHEMBL21628715	0.84	MAOB (0.44)	PLA2G4AALDH1A1RARBLMNACYP1A2
	SCHEMBL21628886	0.84	RARB (0.53)	PLA2G4AALDH1A1SMN1; SMN2RARBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.