SCHEMBL21628909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628705	0.96	ALDH1A1 (0.49)	ALDH1A1HPGDNPSR1MAPTKDM4E
	SCHEMBL21628770	0.91	ALDH1A1 (0.51)	ALDH1A1HPGDNPSR1MAPTKDM4E
	SCHEMBL21628575	0.87	MAPT (0.40)	MAPTKDM4ELMNAMAPK1IGFBP3
	SCHEMBL21628471	0.87	SLC6A2 (0.48)	HPGDMAPTKDM4EMAPK1IGFBP3
	SCHEMBL21628455	0.86	LMNA (0.48)	MAPTKDM4ELMNAMAPK1IGFBP3
	SCHEMBL21628850	0.86	ALDH1A1 (0.51)	ALDH1A1HPGDNPSR1MAPTKDM4E
	SCHEMBL21628831	0.86	MAPT (0.55)	ALDH1A1HPGDNPSR1MAPTKDM4E
	SCHEMBL21628670	0.86	OPRM1 (0.43)	MAPTKDM4EMAPK1IGFBP3SLC6A2
	SCHEMBL21628387	0.85	PARP10 (0.50)	ALDH1A1MAPTKDM4EIGFBP3KMT2A
	SCHEMBL21656474	0.85	LMNA (0.54)	ALDH1A1HPGDNPSR1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.