Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067799 | 0.80 | NPSR1 (0.49) | GAAHTR1FALDH1A1MEN1KMT2A | |
| SCHEMBL6419276 | 0.79 | NPC1 (0.46) | ALDH1A1MEN1KMT2ANPC1MGLL | |
| SCHEMBL171243 | 0.79 | RAB9A (0.55) | ALDH1A1MEN1KMT2ANPC1PKM | |
| SCHEMBL3901564 | 0.77 | KMT2A (0.60) | ALDH1A1MEN1KMT2ANPC1TDP1 | |
| SCHEMBL8689035 | 0.77 | PARP1 (0.55) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL11041250 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ANPC1TDP1 | |
| SCHEMBL15535834 | 0.76 | RAB9A (0.62) | NPC1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL27775502 | 0.75 | MGLL (0.48) | GAAHTR1FMEN1KMT2AMGLL | |
| SCHEMBL2445253 | 0.75 | RAB9A (0.59) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7410095 | 0.74 | PRSS1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022787-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 삼진제약주식회사 | 2020-01-30 | — | — | WO | disclosed |