SCHEMBL216359

SCHEMBL216359

CC[CH]c1nc(OC)cs1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31139826 0.79
SCHEMBL9332066 0.71 GRM4 (0.48)
SCHEMBL12932503 0.69
SCHEMBL2642564 0.69
SCHEMBL6181092 0.69
SCHEMBL2642899 0.67
SCHEMBL9602973 0.67
SCHEMBL11443222 0.67
SCHEMBL2642561 0.67
SCHEMBL5610047 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138810-B UV patternable polymer blend for organic thin film transistor 康宁股份有限公司 2024-05-17 CN disclosed
US-11981679-B2 Tricyclic compounds, compositions and medicinal applications thereof IMPETIS BIOSCIENCES LTD. (IN) 2024-05-14 US disclosed
CN-118001282-A Pharmaceutical composition for cancer treatment 因佩蒂斯生物科学有限公司 2024-05-10 CN disclosed
US-11917897-B2 Photo-patternable organic semiconductor (OSC) polymers for organic thin-film transistors CORNING INCORPORATED (US) 2024-02-27 US disclosed
CN-117222235-A Pseudo-homogeneous photopatternable semiconducting polymer blends for Organic Thin Film Transistors (OTFTs) 康宁股份有限公司 2023-12-12 CN disclosed
WO-2023235181-A1 PSEUDO-HOMOGENEOUS PHOTO-PATTERNABLE SEMICONDUCTING POLYMER BLENDS FOR ORGANIC THIN-FILM TRANSISTORS (OTFT) CORNING INCORPORATED (US) 2023-12-07 WO disclosed
CN-111770926-B Tricyclic compounds, compositions and pharmaceutical uses thereof 因佩蒂斯生物科学有限公司 2023-07-21 CN disclosed
US-11643379-B2 Synthesis of branched alkyl alcohols by Cu(I)-catalyzed C-C coupling between alkyl Grignard reagents and alkyl tosylates CORNING INCORPORATED (US) 2023-05-09 US disclosed
US-20220402927-A1 TRICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF IMPETIS BIOSCIENCES LTD. (IN) 2022-12-22 US disclosed
CN-110730791-B Doping of organic semiconducting polymers with other polymers 康宁股份有限公司 2022-10-21 CN disclosed
US-6713650-B2 ELEVATES ATP BINDING CASSETTE TRANSPORTER 1 EXPRESSION THEREBY INCREASING EFFLUX OF CHOLESTEROL FROM CELLS BY ACTIVE TRANSFER INTO HIGH DENSITY LIPOPROTEINS CV THERAPEUTICS, INC. 2004-03-30 US disclosed
EP-1377283-A2 COMPOUNDS OF THE FORMULA R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS CV THERAPEUTICS, INC. (US) 2004-01-07 EP disclosed
WO-2003103651-A1 COMPOUNDS OF THE FORMU;A R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CAD OR ATHEROSCLEROSIS CV THERAPEUTICS, INC. (US) 2003-12-18 WO disclosed
US-20030229106-A1 A2B adenosine receptor antagonists GILEAD SCIENCES, INC. 2003-12-11 US disclosed
US-20030149060-A1 A2A adenosine receptor antagonists CV THERAPEUTICS, INC. 2003-08-07 US disclosed
US-20030139428-A1 A2B adenosine receptor antagonists GILEAD SCIENCES, INC. 2003-07-24 US disclosed
WO-2003051882-A1 A2A ADENOSINE RECEPTOR ANTAGONISTS CV THERAPEUTICS, INC. (US) 2003-06-26 WO disclosed
WO-2003042214-A2 A2B ADENOSINE RECEPTOR ANTAGONISTS CV THERAPEUTICS, INC. (US) 2003-05-22 WO disclosed
US-20020082257-A1 ABCA-1 Elevating compounds CV THERAPEUTICS, INC. 2002-06-27 US disclosed
WO-2002046141-A2 COUMPOUNDS OF THE FORMULA R1-X-Y-Z-NR2R3 AS ABCA-1 ELEVATING AGENTS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS CV THERAPEUTICS, INC. (US) 2002-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402927-A1 TRICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF ADORA2A, ADORA1, ADORA2B PDE2A 232/4885
US-20030139428-A1 A2B adenosine receptor antagonists ADORA2B, ADORA2A, ADORA1 PDE2A 127/4885
US-20030229106-A1 A2B adenosine receptor antagonists ADORA2B, ADORA2A, ADORA1 PDE2A 127/4885
US-11643379-B2 Synthesis of branched alkyl alcohols by Cu(I)-catalyzed C-C coupling between alkyl Grignard reagents and alkyl tosylates ADH1C, UGCG, ADH1A PDE2A 4025/4885
US-20020082257-A1 ABCA-1 Elevating compounds ABCD3, ABCE1, ABCB4 PDE2A 2024/4885
US-20030149060-A1 A2A adenosine receptor antagonists ADORA2A, ADORA2B, ADORA3 PDE2A 156/4885
US-11981679-B2 Tricyclic compounds, compositions and medicinal applications thereof ADORA2A, ADORA1, ADORA2B PDE2A 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.