Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245856 | 0.82 | MAPT (0.48) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL1261089 | 0.79 | — | — | |
| SCHEMBL237661 | 0.76 | HPGD (0.38) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL919863 | 0.71 | MAOA (0.45) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL4448076 | 0.71 | MAOA (0.40) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL10719244 | 0.71 | MAOA (0.36) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL2523284 | 0.69 | — | — | |
| SCHEMBL15018242 | 0.68 | MAOA (0.52) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL1451915 | 0.68 | MAOA (0.38) | MAOAMAOBHPGDMAPTSMN1; SMN2 | |
| SCHEMBL28003164 | 0.68 | PDE7A (0.39) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144377-A4 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2002-05-02 | — | — | EP | claimed |
| US-6348492-B1 | DERIVATIVES WITH POLYSACCHARIDES LIPASE INHIBITORS. | 2PRO CHEMICAL | 2002-02-19 | — | — | US | claimed |
| US-6342519-B2 | OXETANONE COMPOUNDS COVELENTLY LINKED WITH A POLYSACCHRIDE; LIPASE INHIBITOR | 2 PRO CHEMICAL | 2002-01-29 | — | — | US | claimed |
| EP-1144377-A1 | OXETANONE DERIVATIVES | Mullins, John Jason Gentry (US) | 2001-10-17 | — | — | EP | claimed |
| US-20010012852-A1 | Oxetanone derivatives | BUSS, ROBERT P. | 2001-08-09 | — | — | US | claimed |
| WO-2001032616-A2 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2001032669-A1 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2001032670-A1 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | claimed |
| US-20240018308-A1 | CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF | DOW SILICONES CORP (US) | 2024-01-18 | — | — | US | disclosed |
| EP-4222219-A1 | CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF | Dow Silicones Corporation (US) | 2023-08-09 | — | — | EP | disclosed |
| US-7985519-B2 | Aromatic polycarbonate, electrophotographic photoreceptor, and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2011-07-26 | — | — | US | disclosed |
| US-7625681-B2 | Asymmetric bis-hydroxyenamine compound, electrophotographic photoreceptor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20080199215-A1 | AROMATIC POLYCARBONATE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS | SHARP KABUSHIKI KAISHA (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20060275683-A1 | photoreceptor free of an image defect such as a black spot; polycarbonate, polyether, polyester or polyurethane formed from asymmetric bis-hydroxyenamine p-(p-hydroxyphenylvinyl)phenyl 4-(p-hydroxyphenylvinyl)naphthyl 2,2-diphenylvinylamine | SHARP KABUSHIKI KAISHA (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1144377-A1 | OXETANONE DERIVATIVES | Mullins, John Jason Gentry (US) | 2001-10-17 | — | — | EP | disclosed |
| US-20010012852-A1 | Oxetanone derivatives | BUSS, ROBERT P. | 2001-08-09 | — | — | US | disclosed |
| WO-2001032616-A2 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2001032670-A1 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2001032669-A1 | OXETANONE DERIVATIVES | MULLINS JOHN JASON GENTRY (US) | 2001-05-10 | — | — | WO | disclosed |
| US-3960814-A | SEALS, DINITRILE COMPOUND | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060275683-A1 | photoreceptor free of an image defect such as a black spot; polycarbonate, polyether, polyester or polyurethane formed from asymmetric bis-hydroxyenamine p-(p-hydroxyphenylvinyl)phenyl 4-(p-hydroxyphenylvinyl)naphthyl 2,2-diphenylvinylamine | ALDH1A2, NR2E3, SLC18A1 | MAOA 927/4885MAOB 3320/4885HPGD 384/4885 |
| US-20010012852-A1 | Oxetanone derivatives | CEL, LPL, CYP51A1 | MAOA 179/4885MAOB 168/4885HPGD 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.