Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.37 |
| ▸ | GLRB | P48167 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669624 | 1.00 | ACHE (0.38) | ACHEVCAM1LMNARECQLSMN1; SMN2 | |
| SCHEMBL30488761 | 0.88 | VCAM1 (0.40) | ACHEVCAM1LMNARECQLALDH1A1 | |
| SCHEMBL11622245 | 0.88 | VCAM1 (0.43) | ACHEVCAM1LMNARECQLSMN1; SMN2 | |
| SCHEMBL31176236 | 0.85 | HMGCR (0.35) | VCAM1LMNARECQLALDH1A1GAA | |
| SCHEMBL28794914 | 0.83 | CA2 (0.40) | VCAM1LMNASMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL8832899 | 0.81 | SMN1; SMN2 (0.38) | LMNARECQLSMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL28425957 | 0.80 | ALOX5 (0.39) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL29367920 | 0.80 | ALOX5 (0.39) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL526572 | 0.80 | ALOX5 (0.39) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL28701034 | 0.80 | ALOX5 (0.39) | VCAM1GAAXBP1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678116-B1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | GREAT LAKES CHEMICAL EUROP (CH) | 2012-10-03 | — | — | EP | claimed |
| US-20070208189-A1 | Preparation of Tetrakis [3-(3,5-DI-Tert-Butyl-4-Hydroxy Phenyl) Propionyl Oxymethyl] Methane | ADDIVANT USA, LLC | 2007-09-06 | — | — | US | claimed |
| JP-2007509916-A | — | — | 2007-04-19 | — | — | JP | claimed |
| EP-1678116-A1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | Great Lakes Chemical (Europe) GmbH (CH) | 2006-07-12 | — | — | EP | claimed |
| WO-2005042463-A1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 2005-05-12 | — | — | WO | claimed |
| CN-114133722-B | PC composite material and preparation method and application thereof | 金发科技股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-108495888-B | Additive mixture for stabilizing polyols and polyurethanes | 巴斯夫欧洲公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-107793763-B | High-temperature-resistant heat-conducting silicone grease and preparation method thereof | 佛山市三水铠潮材料科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| EP-1678116-B1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | GREAT LAKES CHEMICAL EUROP (CH) | 2012-10-03 | — | — | EP | disclosed |
| US-7985871-B2 | Preparation of tetrakis[3(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl oxymethyl]methane | CHEMTURA CORPORATION (US) | 2011-07-26 | — | — | US | disclosed |
| US-20100036151-A1 | PREPARATION OF TETRAKIS[3(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONYL OXYMETHYL]METHANE | CHEMTURA CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-7601862-B2 | Preparation of tetrakis [3-(3,5-di-tert-butyl-4-hydroxy phenyl) propionyl oxymethyl] methane | GREAT LAKES CHEMICAL (EUROPE) GMBH (GB) | 2009-10-13 | — | — | US | disclosed |
| US-20070208189-A1 | Preparation of Tetrakis [3-(3,5-DI-Tert-Butyl-4-Hydroxy Phenyl) Propionyl Oxymethyl] Methane | ADDIVANT USA, LLC | 2007-09-06 | — | — | US | disclosed |
| EP-1678116-A1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | Great Lakes Chemical (Europe) GmbH (CH) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042463-A1 | PREPARATION OF TETRAKIS [3-(E,5-DI-TERT-BUTYL-4-HYDROXY PHENYL) PROPIONYL OXYMETHYL] METHANE | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036151-A1 | PREPARATION OF TETRAKIS[3(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONYL OXYMETHYL]METHANE | TERT, HPD, TBL3 | ACHE 1550/4885VCAM1 4675/4885LMNA 3435/4885 |
| US-20070208189-A1 | Preparation of Tetrakis [3-(3,5-DI-Tert-Butyl-4-Hydroxy Phenyl) Propionyl Oxymethyl] Methane | TERT, HPD, TBL3 | ACHE 1602/4885VCAM1 4466/4885LMNA 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.