SCHEMBL21641014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21640928	0.82	SLC6A9 (0.50)	MAPTSLC6A9LMNANPSR1CNR1
	SCHEMBL4793162	0.79	NPSR1 (0.50)	MAPTSLC6A9NPSR1CNR1CNR2
	SCHEMBL21640667	0.78	CYP3A4 (0.52)	MAPTSLC6A9NPSR1CNR1CNR2
	SCHEMBL377735	0.77	KMT2A (0.51)	SLC6A9NPSR1CNR1CNR2HTT
	SCHEMBL1744817	0.75	NPSR1 (0.49)	MAPTSLC6A9NPSR1CNR1CNR2
	SCHEMBL13889298	0.74	SLC6A9 (0.51)	MAPTSLC6A9LMNANPSR1CNR1
	SCHEMBL27717381	0.74	SLC6A9 (0.48)	MAPTSLC6A9NPSR1CNR1CNR2
	SCHEMBL21640167	0.74	SLC6A9 (0.43)	MAPTSLC6A9LMNANPSR1CNR1
	SCHEMBL27717458	0.73	CACNA1A (0.49)	SLC6A9NPSR1CNR1CNR2HTT
	SCHEMBL5283241	0.71	DPP4 (0.41)	SLC6A9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.