SCHEMBL21640928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21640667	0.85	CYP3A4 (0.52)	SLC6A9OPRD1CYP3A4CYP2C19HPGD
	SCHEMBL377735	0.83	KMT2A (0.51)	SLC6A9MTNR1AMTNR1BOPRD1CYP3A4
	SCHEMBL4793162	0.83	NPSR1 (0.50)	SLC6A9HPGDCNR1CNR2HTT
	SCHEMBL21641014	0.82	MAPT (0.56)	SLC6A9CYP3A4CYP2C19HPGDRAB9A
	SCHEMBL27717458	0.82	CACNA1A (0.49)	SLC6A9OPRD1CNR1CNR2HTT
	SCHEMBL27717381	0.81	SLC6A9 (0.48)	SLC6A9OPRD1CYP3A4CYP2C19CNR1
	SCHEMBL13889298	0.81	SLC6A9 (0.51)	SLC6A9CNR1CNR2HTTNPSR1
	SCHEMBL1744817	0.78	NPSR1 (0.49)	SLC6A9HPGDCNR1CNR2HTT
	SCHEMBL5461890	0.77	ALDH1A1 (0.51)	SLC6A9OPRD1CNR1CNR2ALDH1A1
	SCHEMBL2793927	0.76	KMT2A (0.49)	L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.