SCHEMBL377735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4793162	0.87	NPSR1 (0.50)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL13889298	0.84	SLC6A9 (0.51)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL27717381	0.84	SLC6A9 (0.48)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL21640928	0.83	SLC6A9 (0.50)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL1744817	0.82	NPSR1 (0.49)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL27717458	0.80	CACNA1A (0.49)	SLC6A9HTTNPSR1CNR1CNR2
	SCHEMBL21640667	0.80	CYP3A4 (0.52)	KMT2ASLC6A9HTTNPSR1CNR1
	SCHEMBL2793927	0.80	KMT2A (0.49)	KMT2AMEN1MAOB
	SCHEMBL20594076	0.80	KMT2A (0.57)	KMT2ASLC6A9NPSR1CNR1CNR2
	SCHEMBL21441566	0.78	SLC6A9 (0.39)	KMT2ASLC6A9HTTNPSR1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.