SCHEMBL216415

SCHEMBL216415

CCC(C)(C)[C]1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SETD7 Q8WTS6 3/20 0.41
LMNA P02545 5/20 0.40
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 3/20 0.37
HTR1A P08908 3/20 0.37
DRD2 P14416 3/20 0.37
HTR2A P28223 3/20 0.37
SLC6A4 P31645 3/20 0.37
HRH1 P35367 3/20 0.37
HTR6 P50406 3/20 0.37
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030000 0.79 LMNA (0.41) SETD7LMNANPC1CASP3RAB9A
SCHEMBL18241860 0.70 LMNA (0.41) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL2967563 0.70 LMNA (0.41) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL18242887 0.67 LMNA (0.39) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL18241864 0.67 LMNA (0.39) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL218377 0.66 SETD7 (0.42) SETD7LMNANPC1MAPK1RAB9A
SCHEMBL3689047 0.65 LMNA (0.38) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL3686372 0.65 SETD7 (0.39) SETD7LMNACYP1A2CYP2D6HTR1A
SCHEMBL3769766 0.64 MEN1 (0.55) SETD7LMNANPC1MAPK1RAB9A
SCHEMBL18242581 0.64 ALDH1A1 (0.36) SETD7LMNACYP1A2CYP2D6HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
WO-2008140875-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-20 WO disclosed
US-20080287617-A1 Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2008-11-20 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 SETD7 1446/4885LMNA 2508/4885NPC1 3680/4885
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 SETD7 1300/4885LMNA 3684/4885NPC1 3144/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 SETD7 2506/4885LMNA 3055/4885NPC1 3103/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 SETD7 2070/4885LMNA 4060/4885NPC1 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.