Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26251837 | 0.83 | CCR4 (0.56) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL21652283 | 0.81 | CYP19A1 (0.48) | KDM4ESMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL3506580 | 0.81 | HSD17B1 (0.62) | SMN1; SMN2TP53NTMT1POLBLMNA | |
| SCHEMBL21652162 | 0.80 | KDM4E (0.51) | KDM4ESMN1; SMN2MAPTTP53NTMT1 | |
| SCHEMBL10025209 | 0.80 | SREBF2 (0.54) | KDM4ESMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL21652239 | 0.79 | RAB9A (0.46) | KDM4EMAPTTP53NTMT1MEN1 | |
| SCHEMBL3508223 | 0.79 | ALDH1A1 (0.60) | KDM4ESMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5547117 | 0.79 | KDM4E (0.56) | KDM4ESMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL820516 | 0.76 | NTMT1 (0.38) | MAPTNTMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL6528000 | 0.76 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | KDM4E 274/4885SMN1; SMN2 1799/4885MAPT 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.