Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956043 | 0.91 | RXRA (0.30) | RXRARXRBRXRG | |
| SCHEMBL21662016 | 0.81 | HSD11B1 (0.33) | RXRA | |
| SCHEMBL21662167 | 0.70 | — | — | |
| SCHEMBL21662361 | 0.68 | HTR1A (0.33) | — | |
| SCHEMBL21662224 | 0.66 | HSD11B1 (0.38) | RXRA | |
| SCHEMBL24809301 | 0.63 | RXRA (0.40) | RXRARXRBRXRG | |
| SCHEMBL23956041 | 0.63 | HTR1A (0.30) | — | |
| SCHEMBL24809304 | 0.62 | RXRA (0.38) | RXRA | |
| SCHEMBL18015371 | 0.62 | MAPK1 (0.41) | RXRARXRBRXRG | |
| SCHEMBL19794368 | 0.62 | MAPK1 (0.41) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | RXRA 3429/4885RXRB 3685/4885RXRG 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.