Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 3/20 | 0.63 |
| ▸ | DHFR | P00374 | 4/20 | 0.59 |
| ▸ | TYMS | P04818 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.56 |
| ▸ | MTHFD2 | P13995 | 3/20 | 0.55 |
| ▸ | GART | P22102 | 4/20 | 0.54 |
| ▸ | ATIC | P31939 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17097094 | 1.00 | MTHFD1 (0.63) | MTHFD1DHFRTYMSKDM4EMEN1 | |
| SCHEMBL16085830 | 0.93 | MTHFD1 (0.55) | MTHFD1DHFRTYMSKDM4EMEN1 | |
| SCHEMBL26045339 | 0.89 | TYMS (0.55) | MTHFD1DHFRTYMSKDM4EMEN1 | |
| Glutathione SCHEMBL16097636 | 0.82 | MTHFD1 (0.45) | MTHFD1DHFRTYMSKDM4EMEN1 | |
| SCHEMBL28489706 | 0.81 | SOST (0.64) | MTHFD1DHFRTYMSKDM4EMEN1 | |
| SCHEMBL4616964 | 0.80 | MTHFD1 (0.47) | MTHFD1DHFRTYMSSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL1882912 | 0.78 | MTHFD1 (0.86) | MTHFD1DHFRTYMSSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL4727836 | 0.78 | MTHFD1 (0.86) | MTHFD1DHFRTYMSSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL2693607 | 0.78 | MTHFD1 (0.86) | MTHFD1DHFRTYMSSOSTMTHFD2 | |
| Levomefolic Acid SCHEMBL7678398 | 0.78 | MTHFD1 (0.86) | MTHFD1DHFRTYMSSOSTMTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230272442-A1 | 5-METHYLFOLATE PRODUCING MICROORGANISM | CHIFENG PHARMACEUTICAL CO., LTD. (CN) | 2023-08-31 | — | — | US | claimed |
| CN-116096881-A | Microorganism producing 5-methyl folate | 赤峰制药股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| WO-2022013663-A1 | 5-METHYLFOLATE PRODUCING MICROORGANISM | CHIFENG PHARMACEUTICAL CO., LTD. (CN) | 2022-01-20 | — | — | WO | claimed |
| EP-3940071-A1 | 5-METHYLFOLATE PRODUCING MICROORGANISM | Chifeng Pharmaceutical Co., Ltd (CN) | 2022-01-19 | — | — | EP | claimed |
| EP-2781214-A1 | Formulation of amorphous calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) | Chemo Research, S.L. (ES) | 2014-09-24 | — | — | EP | claimed |
| US-8388949-B2 | Compositions comprising pantothenic acid and their use for stimulating appetite | N.V. NUTRICIA (NL) | 2013-03-05 | — | — | US | claimed |
| WO-2024003061-A1 | COMPOSITION FOR THE TREATMENT OF THE HUMAN PAPILLOMAVIRUS INFECTION (HPV) | LO.LI. PHARMA S.R.L. (IT) | 2024-01-04 | — | — | WO | disclosed |
| US-20230272442-A1 | 5-METHYLFOLATE PRODUCING MICROORGANISM | CHIFENG PHARMACEUTICAL CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230272442-A1 | 5-METHYLFOLATE PRODUCING MICROORGANISM | CHIFENG PHARMACEUTICAL CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230181475-A1 | COMPOSITION COMPRISING METHYLFOLATE | ALFASIGMA S.P.A. (IT) | 2023-06-15 | — | — | US | disclosed |
| CN-116096881-A | Microorganism producing 5-methyl folate | 赤峰制药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096881-A | Microorganism producing 5-methyl folate | 赤峰制药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096881-A | Microorganism producing 5-methyl folate | 赤峰制药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20090239826-A1 | COMPOSITIONS AND METHODS FOR THE REGULATION OF HOMOCYSTEINE LEVELS WITHIN THE BODY | FAST BALANCE, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-7429569-B2 | Compositions and methods for the regulation of homocysteine levels within the body | FAST BALANCE, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20070190596-A1 | Synthesis of (6S)-5-methyl-5,6,7,8-tetrahydrofolic acid | CHEMIC LABORATORIES, INC. | 2007-08-16 | — | — | US | disclosed |
| WO-2007084738-A2 | SYNTHESIS OF (6S)-5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID | CHEMIC LABORATORIES, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2005072749-A1 | COMPOSITIONS AND METHODS FOR HOMOCSYTEINE REGULATION | HALEVIE-GOLDMAN, BRIAN, D. (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050171034-A1 | Compositions and methods for the regulation of homocysteine levels within the body | FAST BALANCE, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| EP-0804456-B1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 2002-08-21 | — | — | EP | disclosed |