Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 2/20 | 0.86 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.69 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FPGS | Q05932 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL30051011 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL2693607 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29422840 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL31173596 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL79039 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29616390 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL258787 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL1882912 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL4727836 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL30828726 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112641788-B | Use of 5-methyltetrahydrofolate compositions for improving sleep | 连云港金康和信药业有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-115040520-A | Composition for treating or preventing postpartum depression and application thereof | 连云港金康和信药业有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-109939077-B | Controlled release preparation containing 5-methyltetrahydrofolic acid | 深圳奥萨制药有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-109864978-B | Sustained-release preparation of 5-methyltetrahydrofolic acid and preparation method thereof | 深圳奥萨制药有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114340635-A | Application of 5-methyltetrahydrofolic acid | 连云港金康和信药业有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-119330970-A | Method for recycling and preparing folic acid from (6R) -tetrahydrofolic acid p-toluenesulfonate waste liquid | 湖北楚维药业有限公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20240398808-A1 | DIHYDROFOLATE FOR HYPOGLYCEMIC ACTIVITY | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-12-05 | — | — | US | disclosed |
| CN-114340635-B | Use of 5-methyltetrahydrofolate | 连云港金康和信药业有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117865960-A | Method for synthesizing L-5-methyltetrahydrofolate calcium with enantioselectivity | 江苏欣德瑞医药科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-112641788-B | Use of 5-methyltetrahydrofolate compositions for improving sleep | 连云港金康和信药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-110431141-B | Isomerically pure 18 F-labelled tetrahydrofolate | 默克专利股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115427046-A | Folic acid substance preparation for treating eye diseases | 阿普罗福尔公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115040520-A | Composition for treating or preventing postpartum depression and application thereof | 连云港金康和信药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| US-20220280507-A1 | USES OF 5-METHYLTETRAHYDROFOLATE AND ITS COMPOSITION | LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO., LTD. (CN) | 2022-09-08 | — | — | US | disclosed |
| CN-109939077-B | Controlled release preparation containing 5-methyltetrahydrofolic acid | 深圳奥萨制药有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109864978-B | Sustained-release preparation of 5-methyltetrahydrofolic acid and preparation method thereof | 深圳奥萨制药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112294821-B | Application of 5-methyltetrahydrofolic acid and composition thereof | 连云港金康和信药业有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114340635-A | Application of 5-methyltetrahydrofolic acid | 连云港金康和信药业有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-6441168-B1 | Stable crystalline salts of 5-methyltetrahydrofolic acid | EPROVA AG (CH) | 2002-08-27 | — | — | US | disclosed |