Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 2/20 | 0.86 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.69 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FPGS | Q05932 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL30051011 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL2693607 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29422840 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL31173596 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL7678398 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL79039 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29616390 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL258787 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL1882912 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL30828726 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260117270-A1 | TETRAHYDROFOLATE METHYLTRANSFERASE MUTANT, ENCODING GENE AND APPLICATIONS THEREOF | ZHEJIANG SHENGDA BIO-PHARM CO., LTD. (CN) | 2026-04-30 | — | — | US | claimed |
| US-20260063623-A1 | METHODS OF ASSESSING METABOLIC FLUX | UNIV MICHIGAN REGENTS (US) | 2026-03-05 | — | — | US | claimed |
| EP-4688828-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF | Jubilant DraxImage Inc. (CA) | 2026-02-11 | — | — | EP | claimed |
| EP-4602365-A2 | METHODS OF ASSESSING METABOLIC FLUX | The Regents of The University of Michigan (US) | 2025-08-20 | — | — | EP | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2025096781-A1 | METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED SKIN REGIMENS | VIBRANT HOLDINGS, LLC (US) | 2025-05-08 | — | — | WO | claimed |
| CN-119438463-B | Method for measuring total folic acid of red blood cells by liquid chromatography-tandem mass spectrometry | 西湖维泰(杭州)诊断技术有限公司 | 2025-04-22 | — | — | CN | claimed |
| EP-4531862-A2 | COMBINATION OF SMALL MOLECULE DRUG CONJUGATE AND CAR-EXPRESSING CYTOTOXIC LYMPHOCYTES AND METHODS OF USE | Purdue Research Foundation (US) | 2025-04-09 | — | — | EP | claimed |
| CN-119709678-A | Tetrahydrofolate methyltransferase mutant, coding gene and application thereof | 浙江圣达生物药业股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119438463-A | Method for measuring total folic acid of red blood cells by liquid chromatography-tandem mass spectrometry | 西湖维泰(杭州)诊断技术有限公司 | 2025-02-14 | — | — | CN | claimed |
| WO-2023031860-A1 | COMPOSITIONS, KITS, AND METHODS TO PROVIDE SYNERGISTIC AND/OR ADDITIVE EFFECTS FROM COMPRISED INGREDIENTS FOR THE PREVENTION, TREATMENT AND MANAGEMENT OF NAUSEA AND VOMITING. | PATEL, Natvarlal Hargovinddas (IN) | 2023-03-09 | — | — | WO | claimed |
| EP-4138809-A1 | TREATMENT OF CONDITIONS ASSOCIATED WITH THYROID HORMONE | Scott III, Linzy O. (US) | 2023-03-01 | — | — | EP | claimed |
| WO-2022269064-A1 | NAD-AUGMENTATION THERAPY FOR PARKINSON'S DISEASE | VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) | 2022-12-29 | — | — | WO | claimed |
| CN-113603691-B | Preparation process of L-5-methyl tetrahydrofolic acid calcium | 连云港冠昕医药科技有限公司 | 2022-08-26 | — | — | CN | claimed |
| WO-2022144804-A1 | METHOD FOR DETERMINING B VITAMINS AND THEIR VITAMERS | WATERS TECHNOLOGIES CORPORATION (US) | 2022-07-07 | — | — | WO | claimed |
| US-20220205961-A1 | METHOD FOR DETERMINING B VITAMINS AND THEIR VITAMERS | WATERS TECHNOLOGIES CORPORATION (US) | 2022-06-30 | — | — | US | claimed |
| EP-2773355-B1 | METHODS, FORMULATIONS, AND KITS FOR RAPIDLY REPLETING FOLATE LEVELS IN WOMEN | SOUTH ALABAMA MEDICAL SCIENCE FOUND (US) | 2022-06-08 | — | — | EP | claimed |
| CN-113403355-B | Method for producing L-5-methyltetrahydrofolic acid by biological method | 山东大学 | 2022-05-31 | — | — | CN | claimed |
| US-11313868-B2 | Methods of detecting anti-folic acid antibodies and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-04-26 | — | — | US | claimed |
| WO-2022040740-A1 | METHOD OF TREATING DEPRESSION AND/OR ANXIETY, AND/OR SYMPTOMS ASSOCIATED THEREWITH | State of Mind Australasia Pty Ltd (AU) | 2022-03-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260063623-A1 | METHODS OF ASSESSING METABOLIC FLUX | PC, SLC2A1, SLC2A4 | MTHFD1 750/4885DHFR 2642/4885SOST 1494/4885 |
| US-20260117270-A1 | TETRAHYDROFOLATE METHYLTRANSFERASE MUTANT, ENCODING GENE AND APPLICATIONS THEREOF | MTHFD2, MTHFD1, DHFR | MTHFD1 2/4885DHFR 3/4885SOST 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.