Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.43 |
| ▸ | CTSK | P43235 | 14/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504982 | 0.86 | CTSS (0.46) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL26227418 | 0.84 | CTSS (0.43) | CTSSCTSKCTSBCTSL | |
| SCHEMBL20997615 | 0.83 | CTSS (0.41) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL17476298 | 0.81 | KMT2A (0.40) | CTSSCTSKCTSBCTSLKMT2A | |
| SCHEMBL20997532 | 0.81 | CTSS (0.44) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL7995586 | 0.73 | CTSK (0.54) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL7943806 | 0.69 | CTSS (0.49) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL15932451 | 0.68 | CTSS (0.40) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL17474200 | 0.68 | CTSS (0.42) | CTSSCTSKCTSBCTSLMMP13 | |
| SCHEMBL30570497 | 0.68 | CTSS (0.42) | CTSSCTSKCTSBCTSLMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604308-A1 | SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | Boehringer Ingelheim International GmbH (DE) | 2020-02-05 | — | — | EP | disclosed |