Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 8/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | VHL | P40337 | 3/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386468 | 0.79 | KDR (0.37) | HDAC3HDAC1KDM4EALDH1A1GAA | |
| SCHEMBL21386473 | 0.73 | KDR (0.64) | HDAC1KDRFLT3HDAC6 | |
| SCHEMBL21668695 | 0.73 | KDR (0.64) | HDAC1KDRFLT3HDAC6 | |
| SCHEMBL13973213 | 0.65 | TPSAB1 (0.55) | HDAC3HDAC1ALDH1A1GAAHDAC2 | |
| SCHEMBL25793510 | 0.63 | CASP2 (0.55) | ALDH1A1 | |
| SCHEMBL29967987 | 0.63 | MEN1 (0.37) | HDAC3HDAC1KDRFLT3HDAC2 | |
| SCHEMBL25030179 | 0.62 | CASP2 (0.50) | ALDH1A1 | |
| SCHEMBL27657561 | 0.61 | KDR (0.44) | ALDH1A1KDRFLT3 | |
| SCHEMBL21727789 | 0.61 | CASP2 (0.48) | ALDH1A1 | |
| SCHEMBL23616303 | 0.60 | CASP2 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | HDGF, MKI67, LITAF | HDAC3 3496/4885HDAC1 2833/4885KDM4E 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.