SCHEMBL2167255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL432657	0.93	KMT2A (0.49)	KMT2AMEN1NPSR1SMN1; SMN2NPC1
	SCHEMBL12016597	0.85	CYP19A1 (0.50)	KMT2AMEN1NPSR1NPC1RAB9A
	SCHEMBL2152993	0.83	TBXAS1 (0.38)	CYP19A1CYP11B1CYP11B2GRIN2BPOLB
	SCHEMBL1621471	0.83	CYP19A1 (0.42)	KMT2AMEN1NPSR1CYP19A1CYP11B1
	SCHEMBL1622205	0.81	CYP11B1 (0.50)	KMT2AMEN1CYP19A1CYP11B1CYP11B2
	SCHEMBL4059533	0.79	P2RX4 (0.48)	SMN1; SMN2NPC1RAB9AGRIN2BP2RX4
	SCHEMBL4027132	0.78	HMOX1 (0.48)	KMT2AMEN1CYP2C9CYP2C19CYP3A4
	SCHEMBL15591339	0.78	TBXAS1 (0.38)	KMT2AMEN1NPSR1CYP19A1CYP11B1
	SCHEMBL17181088	0.77	CA12 (0.46)	KMT2ACYP19A1CYP11B1CYP11B2CYP2D6
	SCHEMBL23764025	0.77	LMNA (0.51)	KMT2AMEN1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.